Anti-VEGF Therapy

Many retinal conditions can be treated using medications that are injected into the eye. The needle is injected directly into the sclera (the white part of the eye) and into the vitreous humor, the gel in the middle of the eye. This procedure is generally performed in-office using drops to numb the eye.

Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Injections

The most common types of eye medications that are administered via injection are anti-vascular endothelial growth factor (anti-VEGF) medications. Anti-VEGF medications are used to slow the growth of abnormal blood vessels or prevent blood vessels from leaking fluid in the eye. The most well-known anti-VEGFs available are Avastin, Lucentis, Eylea, Eylea HD and Vabysmo.

Abnormal blood vessels are associated with several retinal conditions, including wet age-related macular degeneration (AMD) and diabetic retinopathy. The abnormal blood vessels leak and bleed into the retina, which can impair vision. The anti-VEGF medications help to halt or minimize abnormal blood vessel growth and leakage, thereby helping to stabilize vision. For many patients, anti-VEGF injections can even improve vision.

Repeat injections are usually required, especially for chronic conditions such as AMD and diabetic retinopathy. Dr. Fern will discuss your long-term treatment options during your clinical examination.

When Eye Injections Are Recommended

Eye injections are used to treat a wide range of retinal conditions, including:

  •     Wet age-related macular degeneration
  •     Diabetic retinopathy
  •     Retinal vein occlusion
  •     Diabetic macular edema (swelling of the retina)

What to Expect During the Eye Injection Procedure

Although the idea of getting eye injections may seem intimidating, most patients experience little to no discomfort or pain during the procedure. Knowing what to expect helps many patients feel more at ease before the procedure begins. Below are the general steps of an eye injection procedure:

  1. First, the ophthalmic technician will apply a local anesthetic on the eye, usually with a drop. This will numb the eyes and prevent pain during the injection.
  2. Your eyes will be cleaned with an antiseptic to prevent bacterial infection.
  3. Next, Dr. Fern will then use a speculum to keep your eyelid open during the procedure.
  4. Once your eyelid has been secured, Dr. Fern will instruct you to look in the direction away from where the needle will be administered.
  5. Using a very thin needle, Dr. Fern will inject the medication thru your sclera into the eye. You may feel a slight pressure.

The procedure is very quick, typically taking only about 5 minutes to perform.

Recovery After Eye Injections

After receiving an eye injection, you may experience eye irritation. Using topical artificial tears like Preservative Free Refresh every 1-2 hours for the rest of the day after the injection may improve your comfort. In some cases, you may develop a blood spot at the injection site of the eye, also known as a subconjunctival hemorrhage. Although this might look scary, it usually clears up within a 2-3 weeks. It is common to see floaters after the injection, which typically improve over a few days.

In the vast majority of cases, recovery after eye injection is simple and without complication. However, there is a small risk--less than 1 in 5,000--of infection or vision loss after an injection. If you experience any of the following symptoms after having eye injections, it’s important that you contact Dr. Fern immediately:

  •     Pain and discomfort in the injected eye
  •     Decreased vision
  •     Increased light-sensitivity